Since I feel like the OP's point is not visually explained well, here's what I would like to see happen...
Currently, I have a sequence like so:
The hotbar, by default, shows Force Opportunity in the icon.
This works as intended. Every 2 seconds, the sequence resets and skips abilities on cooldown.
However, let's say I add "Cull the Weak" to this setup. This is an ability that will contextually activate depending on the targets' health.
If I add this ability to my 10s rotation button, I can no longer activate the rest of the sequence - Cull the Weak will never activate until my target reaches 50% health, and thus, the rest of the sequence will never activate.
Cull the Weak should be considered an 'ability on cooldown' while it is unusable. That doesn't appear to be happening, and breaks functionality.
Under this setup, there is no automation. I still have to be at the keyboard and hit the sequence. For the record, NB never had AFK automation in it either - but instead, NB extended scripted conditionals beyond the realm of what a sequencer did.
The above screenshot is tame in comparison to NB and would be the appropriate use case. Besides, others have made more malicious addons that do that way better than NB did.
I am not asking for duration conditionals, or 'cast heal when target is below x' style conditionals. I am asking for the ability to keybind less things - simply because I am a software engineer who has a permanent repetitive strain injury. Mind you, 4 years of my life of that carpal tunnel was spent developing for Return of Reckoning.
Please consider adding this in as a feature.