Return of Reckoning

Pressing V or B does nothing. Pressing the corresponding icons at the top of the screen also does nothing.

Tried disabling addons and relogging, no dice. Tried resetting the interface, also no dice.

Any ideas?

I would say check your binds, but if you cant click on them either that's probably not the issue

Sounds like a known problem when you first start the game.
Close game including launcher and let it download some more files